Clinical trial patient recruitment that fills enrollment targets.

Brighter Click delivers full-funnel digital recruitment for CROs, sponsors, and research sites. From IRB-ready ad creative to qualified patient referrals and site-level tracking, we help you enroll faster, at a lower cost per randomized patient.

$15M+ ad spend managed6 simultaneous trialsIRB-ready creative

Free PATIENT RECRUITMENT STRATEGY CALL

Behind on enrollment targets?

We build paid media campaigns that reach eligible participants around your trial sites. Talk to our team about geo-targeted paid media strategies built for sponrs, CROs, and research sites.

G
Google Partner
M
Meta Business Partner
C
Meta Certified Creative Strategy
$
$15M+ in Clinical Trial Ad Spend Managed
6
6 Simultaneous Active Trials
45.9%
Decrease in Cost Per Anonymized Patient
91.5%
Increase in Click-to-Conversion Ratio
$20-39
CPL Range Across Therapeutic Areas
6
Simultaneous Active Trials Managed

Case Study: Adams Clinical

45.9% Decrease in Cost Per Anonymized Patient While Scaling to $600K/Month

Adams Clinical needed to scale patient recruitment spend from $360K to $600K per month across 6 simultaneous clinical trials while maintaining cost efficiency. Our team deployed a performance creative strategy across Meta and Google, with continuous creative testing and funnel-stage optimization from click through to qualified referral.

Read the Full Case Study

The Problem

The clinical trial patient recruitment challenge

Enrollment delays are the single largest cost driver in clinical development. Traditional referral networks are no longer sufficient for enrollment at scale. Digital patient recruitment is now essential infrastructure.

80%
of clinical trials fail to meet enrollment timelines
$8M
per day in opportunity cost from trial delays on blockbuster drugs
30%
of total trial budget consumed by patient recruitment
37%
of trial sites under-enroll; 11% enroll zero patients

Our Approach

How Brighter Click approaches patient recruitment

We do not stop at the click. Our methodology covers the full enrollment funnel, from trial analysis through site referral and randomization tracking. Every stage maps to the metrics sponsors and CROs actually purchase on.

1

Trial Analysis and Audience Mapping

Study the protocol, define the ideal patient profile, map condition-specific demographics, and analyze competing trials recruiting for the same population.

2

IRB-Ready Creative Production

Develop ad creative that meets IRB and FDA 21 CFR Part 50 requirements with medical copy QC and localization support.

3

Multi-Platform Paid Media Launch

Deploy across Meta and Google with condition-specific targeting, geographic precision near trial sites, and cost-per-screened-patient optimization.

4

Screening Funnel and Qualification

Pre-screening against inclusion/exclusion criteria, 5-minute speed-to-lead callback, qualified referral routing to trial sites.

5

Site Referral Tracking and Reporting

Secure lead routing to sites with status tracking from referral through screening, consent, and randomization.

Therapeutic Areas

Therapeutic areas we recruit for

Each condition demands a different targeting strategy, creative approach, and regulatory posture. We build recruitment campaigns specific to the patient population, not generic health ads.

CNS and Neurology

Alzheimer's, Parkinson's, MS, depression, anxiety. Sensitivity-aware messaging, caregiver pathways, stigma-conscious creative.

Oncology and Rare Disease

Hyper-targeted campaigns for low-prevalence conditions. Lookalike audiences from condition communities, caregiver targeting, geographic precision near trial sites.

Dermatology

Psoriasis, eczema, acne. Visual conditions suited to social media creative. Before-and-after awareness framing within IRB guidelines.

Cardiovascular and Metabolic

Diabetes, heart disease, obesity. Large patient populations with high competition for enrollment. Scale-ready campaign architecture.

Ophthalmology

Diabetic retinopathy, macular degeneration. Proven recruitment campaigns with $2,833 cost per trial-qualified candidate benchmarks.

Additional Indications

We have developed recruitment campaigns across multiple therapeutic areas. Contact us for indication-specific feasibility.

Recruitment by Phase

Recruitment strategy by trial phase

Different phases require fundamentally different approaches to targeting, messaging, and scale.

Phase I

Healthy Volunteers

Broad demographic targeting, compensation-led messaging, high-volume screening funnels.

Phase II

Condition-Specific

Smaller scale, stricter I/E criteria, condition-education creative, tighter geographic targeting.

Phase III

Large-Scale Enrollment

Multi-site coordination, diversity requirements, rescue study capability, enrollment velocity at scale.

Phase IV

Post-Market Evidence

Broader eligibility, real-world evidence collection, lower-intensity screening funnels.

Services

Our patient recruitment services

Full-funnel capabilities from ad creative through randomization reporting. Every service links to measurable enrollment outcomes.

META

Meta Ads (Facebook and Instagram)

Condition-specific interest targeting, lookalike audiences from screened patient lists, IRB-compliant ad copy.

GOOGLE

Google Ads

Capture patients searching condition clinical trial near me. Geographic targeting near trial sites, cost-per-screened-patient optimization.

IRB

IRB-Ready Ad Creative

Compliance-reviewed creative production for regulated verticals. A/B testing frameworks and creative analytics to identify what drives enrollment.

QF

Pre-Screening and Qualification

IRB-approved screening scripts administered within 5 minutes of form submission. Inclusion/exclusion filtering, qualified referral delivery to sites.

RT

Site Referral Tracking

Secure routing of qualified candidates to trial sites with status tracking: referred, screened, consented, randomized.

ER

Enrollment Reporting

Weekly funnel-stage dashboards: spend, leads, contact rate, qualified, referred, screened, consented, randomized. Cost-per at each stage.

Portfolio

Clinical trial ad creative examples

Every clinical trial ad we produce is reviewed for regulatory compliance and tested against performance benchmarks.

Alzheimer's Prevention Trial
Memory Loss Drug Trial
Depression Trial

Diversity Recruitment

Diversity in clinical trial recruitment

FDA Diversity Action Plan guidance makes diverse enrollment a regulatory expectation. Digital-first recruitment is inherently suited to reaching underrepresented populations. Our capabilities include multilingual ad creative with in-country copywriters across English, Spanish, German, French, and Italian. Culturally sensitive messaging developed by creators from diverse demographics across the U.S., Latin America, and the EU. And precision targeting in underserved geographic communities, not just major metro areas.

In-House vs. Outsourced

Why outsource clinical trial marketing?

S

Speed to Launch

Existing creative workflows and platform certifications versus building an internal team from scratch.

M

Multi-Platform Expertise

Meta, Google, and TikTok managed by specialists without hiring three separate platform leads.

B

Cross-Trial Benchmarks

Performance data from campaigns across multiple trials and therapeutic areas informs every new launch.

L

Closed-Loop Advantage

The team producing the creative is the same team running the media and optimizing the funnel. No handoff gaps.

Decentralized Trials

Marketing for decentralized and hybrid trials

When patients can participate remotely, the recruitment strategy shifts entirely to digital channels. Our digital-first model is built for this. Nationwide geographic targeting unconstrained by trial site radius. Telehealth-compatible screening funnels. Digital consent pathways. Virtual trial awareness campaigns that reach patients wherever they are, not just within driving distance of a clinic.

Creative Intelligence Dashboard screenshot placeholder
Powered by DataAlly

Creative intelligence for clinical trials

Most agencies lose performance insights in spreadsheets. We built DataAlly to centralize creative intelligence across every trial we manage. It categorizes live ad performance across nine dimensions, connecting creative decisions to enrollment outcomes, not just media metrics.

DataAlly is also an independent clinical trial marketing resource, publishing research and agency comparisons used by sponsors and CROs evaluating recruitment partners.

Results

Proven across therapeutic areas

$20-39
CPL Across Memory, Anxiety, Depression
$1,545
Per Qualified Candidate (Alzheimer's Prevention)
$2,833
Per Qualified Candidate (Diabetic Retinopathy)
$600K+
Monthly Recruitment Media Managed

Aggregate data across clinical trial recruitment campaigns. Individual results vary by therapeutic area, trial phase, and geography.

Compliance

Built for regulated industries

We operate under the compliance framework that pharma procurement teams audit for.

IRB Direct Submission

Registered on WCG Connexus and Advarra CIRBI. With sponsor designation, we submit recruitment materials directly and manage approvals end to end.

HIPAA-Grade Data Handling

BAAs signed with every vendor in the data chain. No Meta pixel or third-party scripts on pages collecting health information.

GCP-Trained Team

ICH GCP training certificates for all client-facing personnel. SOPs, training logs, and CAPA process documented and auditable.

Adverse Event Escalation

AE identification SOP with 24-hour escalation to sponsor pharmacovigilance. Every channel monitored: ad comments, inboxes, calls.

TCPA-Consented Outreach

Prior express consent captured at every form. DNC scrubbing, immediate opt-out honoring, AI disclosure at call start, consent records retained 4+ years.

EU Ethics and Localization

In-country copywriter roster for DE, ES, IT, FR, UK. Ethics committee submission support. GDPR data handling with DPAs.

FAQ

Frequently asked questions

What platforms do you run clinical trial ads on?
Meta (Facebook and Instagram), Google Search and Display, TikTok, and programmatic. Platform mix depends on the therapeutic area, patient demographics, and trial phase.
How do you handle IRB approval for ad materials?
We are registered on WCG Connexus and Advarra CIRBI. With sponsor designation, we submit recruitment materials directly to the IRB and manage the approval cycle end to end.
What does a typical cost per lead look like?
CPLs vary significantly by therapeutic area and trial requirements. Across CNS trials we typically see $20-39 CPL. We share benchmarks specific to your indication during the strategy call.
Do you work with CROs or directly with sponsors?
Both. We work directly with pharmaceutical sponsors and as a recruitment vendor within CRO-managed trials.
How quickly can you launch a recruitment campaign?
Once IRB-approved materials are in hand, we can launch media within 5 business days.
What is your adverse event reporting process?
We have a documented AE identification SOP with 24-hour escalation to sponsor pharmacovigilance. Every patient-facing channel is monitored.
Can you recruit for international or multi-country trials?
Yes. We have in-country copywriter rosters for DE, ES, IT, FR, and UK markets with ethics committee submission support and GDPR-compliant data handling.
How do you ensure HIPAA compliance in ad campaigns?
BAAs are signed with every vendor in the data chain. No Meta pixel or third-party tracking scripts are placed on pages collecting protected health information.
What reporting do you provide to trial sponsors?
Weekly performance dashboards with CPL, qualified candidate volume, screen-to-enroll ratios, and geographic distribution. Monthly strategic reviews with creative performance analysis.
Do you handle pre-screening and qualification?
Yes. We build custom pre-screening questionnaires based on inclusion/exclusion criteria, manage inbound lead qualification, and can integrate with your CTMS or EDC system.

Start your recruitment strategy

Book a 20-minute call with our clinical trial marketing team. We will discuss your trial, how many review your protocol, discuss your enrollment targets, and outline a recruitment strategy.

1
Share your trial details
Protocol phase, therapeutic area, target enrollment
2
Get a custom recruitment plan
Platform strategy, creative approach, projected timeline
3
Launch within days
IRB submission, creative production, media activation
First Name
First name
Last Name
Last name
Work Email
you@company.com
Company / Organization
Company name
Therapeutic Area
e.g. Oncology
Trial Phase
Phase I-IV
Book Strategy Call

Related Resources

Book A Strategy Call
arrow